UNITED BIOTECH (P) LTD.


Docetaxel Injection Concentrate

Product Code : 11

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Product Specification
Docetaxel Injection Concentrate:
  • Its cytotoxic activity is through enhancement and stabilization of microtubule assembly leading to an arrest of the cell cycle at the G2/M Phase.
  • Has high binding affinity to rubulin and is a potent promoter of microtubule formation.
  • Helps improve survival rate as compared to other regimens.
  • Induces tumour cell dealth by apoptosis and also have antiangiogenic and has immunostimulating properties.
  • Demonstrated in vitro and in vivo additive and synergistic effects when combined with a large spectrum of anticancer therapies such as new cytotoxic agents, specific signal transduction drugs, antiangiogenic drug, gene therapy etc.
  • As single agent treatment effective in elderly patients with advanced breast cancer.
  • Docetec enhance the cytotoxicity of anthracyclines by increasing.intracellular drug accumulation.
  • Men with advanced, incurable prostate cancer can benefit from Docetec.
Indications:
  • Brest cancer
  • Non-small cell Lung cancer
  • Prostate cancer
  • Gastric Adenocarcinoma
Dosage & Administration:
Breast Cancer
60-100 mg/m2 administered intravenously over 1 hour every 3 weeks
Non-Small Cell Lung Cancer
75 mg/m2 administered intravenously over 1 hour every 3 weeks
Prostate cancer
75 mg/m2 every 3 weeks as a 1 hour infusion

75 mg/m2 as a 1 hour intravenous infusion, followed by:
  • Cisplatin 75 mg/m2, as a 1 to 3 hour intravenous infusion (both on day 1 only)
  • Fluorouracil 750mg/m2, per day given as a 24-hour continuous intravenous infusion for 5 days.

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