UNITED BIOTECH (P) LTD.


Tecoplan

Product Code : 08

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Product Specification
Tecoplan:
  • Powerful Bactericidal
  • Activity against both anaerobic and aerobic gram positive pathogens
  • No Cross resistance with other class of antibiotics
  • Exhibits Synergy with Aminoglycosides. Bactericidal Synergy in vitro with aminoglycosides against enterococci (group D streptococci) and staphylcocci has been demonstrated
  • Active against both Methicillin sensitive and Methicillin resistant Staphylococcus aureus
  • Effective against Listeria monocytogenes, Corynebacterium spp. Clostridium spp. and anaerobic gram positive cocci.
Clinical Outcome / Teicoplanin Predose Concentration:
S. aureus Septicemia (n = 80)
90% (Cmax > mg/L)
S. aureus Endocraditis (n = 21)
91% (Cmax > mg/L)

Indications:
  • Serious infections due to staphylococci or streptococci
  • Bone - Osteomyelitis
  • Joint - Septic Arthritis
  • Blood - Non cardiac Bacteraemia, Septicaemia
  • Febrile Neutropenia
Dosage & Administration:
Can be given both IM or IV
Adults:
Septicaemia / Bacteraemia /
Acute or Chronic Osteomyelitis
400 mg  IV every 12 hours for 3 doses
then 400 mg once daily as maintenance dose
Septic Arthritis
800 mg IV every 12 hours for 3 doses than
800 mg once daily as maintenance dose

Pediatric Patients (Children aged 2 Months - 16 yrs.):
For Severe infections & infections
in Neutropenic patients
10 mg/kg IV every 12 hrs. for 3 doses and then 10
mg/kg IV as a single dose once daily
For Moderate Infections
10 mg/kg every 12hrs. for first 3 doses and then
6mg/kg as IV or IM as single dose once daily

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