UNITED BIOTECH (P) LTD.
Netmicin
Product Code :
02
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Product Specification
Netmicin:
Offers:
Wide In-vitro Spectrum and Lowered Toxicity profile
Comparable Penetration Into the CSF
Enhanced in-vitro bactericidal activity
Presence of only three free amino groups
A 100 fold increase in inoculumn size results in reduced MIC as well as MBC value with netilmicin than with amikacin or gentamicin.
Exhibits highest sensitivity for Acinetobacter than amikacin and amoxycillinclavulanic acid
Netilmicin and Piperacillin were found to be the most effective drugs for S. aureus and P. aeruginosa.
OD Dose Provides:
Minimal renal cortical uptake and thus decreases nephroloxicity
Low perilymph levels results in lesser incidence of ototoxicity
Good Post antibiotic effect which suppresses bacterial regrowth even at sub MIC drug level
Indications:
Septicemia
Febrile Neutropenia
Intra Abdominal Sepsis
Endocarditis
Meningitis
Dosage:
Adults Complicated UTIs
4 to 6 mg/kg/day
Serious life threatening infections
6 to 7.5 mg/kg/day
Children (6 weeks through 12 years. of age)
6 to 7.5 mg/kg/day
Premature of full term Neonates (<1 week of age)
6 mg/kg/day
Neonates over one week of age
7.9 to 9 mg/kg/day
Maintenance Dose every 8 hours = Observed CCr* / Normal CCr x Usual Maintenance Dose
CCr = Creatinine clearance rate in mL/min/1.73m
2
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